This Graduate Programme focuses on population vulnerability from a holistic, ecosystem-based perspective. It offers an in-depth reflection on the research methods used not only to measure but also to prevent and reduce vulnerabilities, by integrating a multidisciplinary approach and a temporal perspective (life courses, disease trajectories, social and environmental dynamics). Emphasis will be placed on the co-construction of knowledge with patients, service users, or expert students. Unique in France, this program brings together students from six Master’s level (M1) tracks, organized into multidisciplinary groups. Following a day of theoretical training and presentations of research conducted at the University of Lille using qualitative, quantitative, and mixed methods, each group will develop a research project supported by experts, highlighting interdisciplinarity and innovation in response to major societal challenges.